SKU-Pack Size | Availability | Size | Price | |
EAB21664-100UL | In Stock | 100ul | €297.70 | |
EAB21664-200UL | In Stock | 200ul | €479.70 |
Please select the country you are in to find your local distributor. |
Cambiotech | Phone£º+44 (0) 188 448801 | |
Lanwades Business Park, | E-mail£ºinfo@cambiotech.com | |
Ireland | Kobenhavn K, Ireland | Web£ºwww.cambiotech.com |
Product Information | |
Applications | WB, IP, IHC-P, IF/ICC, FC |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000¡¡ IP=1:10-100¡¡ IHC-P=1:50-200¡¡ IF/ICC=1:100-500¡¡ FC=1:10-100 |
MW (kDa) | 62 |
Conjugate | Unconjugate |
Specificity | Cortactin Rabbit Monoclonal Antibody detects endogenous levels of Cortactin protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | Amplaxin; Oncogene SRC8; Src substrate cortactin; CTTN; EMS-1; EMS1; p80/85 src substrate; Src-8 |
Gene Aliases | CTTN |
UniProt ID | |
Entrez Gene ID |
Product Description | |
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using Cortactin Rabbit Monoclonal Antibody (EAB21664) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: Hela Lane2: A431 Predicted band size: 62 kDa; Observed band size: 75 kDa |
Specific Protocols | |