SKU-Pack Size | Availability | Size | Price | |
EAB21454-100UL | In Stock | 100ul | ¥2290.00 |
Please select the country you are in to find your local distributor. |
北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IP, IHC-P, IF/ICC |
Species Reactivity | Human |
Host / Isotype | Rabbit IgG |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 |
MW (kDa) | 62 |
Conjugate | Unconjugate |
Specificity | PKR Rabbit Monoclonal Antibody detects endogenous levels of PKR protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | Eukaryotic translation initiation factor 2 alpha kinase 2; PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83; EIF2AK2 |
Gene Aliases | EIF2AK2 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
PKR also known as EIF2AK2 is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. |
Product Image Gallery | |
Western blot analysis of extracts on Hela, MCF7 cells, using PKR Rabbit Monoclonal Antibody (EAB21454) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 62 kDa; Observed band size: 68 kDa |
Specific Protocols | |