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PRP19 Rabbit Monoclonal Antibody
Catalog #£ºEAB22614
  SKU-Pack Size Availability Size Price
EAB22614-100UL In Stock 100ul €297.70
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Cambiotech Phone£º+44 (0) 188 448801
Lanwades Business Park, E-mail£ºinfo@cambiotech.com
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Product Information
Applications WB, IHC-P, IF/ICC, FC
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Monoclonal
Applications Dilutions WB=1:500-2000
IHC-P=1:50-200¡¡
IF/ICC=1:50-200¡¡
FC=1:10-100
MW (kDa) 55
Conjugate Unconjugate
Specificity PRP19 Rabbit Monoclonal Antibody detects endogenous levels of PRP19 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Pre-mRNA processing factor 19; PSO4; SNEV; PRP19; UBOX4; hPSO4; NMP200; PRPF19
Gene Aliases PRPF19
UniProt ID

Q9UMS4

Entrez Gene ID

27339

Product Description

PRP19 is part of the PRP19-associated complex, which is vital for the stable association of U5 and U6 snRNPs with the spliceosome after the release of U4. PRP19 interaction with the spliceosome not only facilitates the remodeling of the U6/5 splice site interaction but also leads to the destabilization of Lsm proteins, allowing U6 to engage more effectively with the intron sequence. Understanding PRP19 function is important because any dysregulation in splicing can lead to various diseases, including cancer and neurodegenerative disorders.

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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