Recombinant Antibodies - Phospho-TrkB (Tyr817) Rabbit Monoclonal Antibody

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Phospho-TrkB (Tyr817) Rabbit Monoclonal Antibody

Catalog #：EAB21609

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21609-100UL	In Stock	100ul	￡251.90

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IP, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IP=1:10-100　 IHC-P=1:50-200　 IF/ICC=1:50-200
MW (kDa)	92
Conjugate	Unconjugate
Specificity	Phospho-TrkB (Tyr817) Rabbit Monoclonal Antibody detects endogenous levels of TrkB protein only when phosphorylated at Tyr817.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Neurotrophic receptor tyrosine kinase 2; OBHD; TRKB; DEE58; trk-B; EIEE58; GP145-TrkB; NTRK2
Gene Aliases	NTRK2
UniProt ID	Q16620
Entrez Gene ID	4915

Product Description

TrkB also known as NTRK2 is a member of the tropomyosin receptor kinase family and serves as a crucial tyrosine kinase receptor for neurotrophic factors including brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3). These interactions are fundamental for the development, maintenance, and function of the central and peripheral nervous systems, playing a vital role in neuronal survival, differentiation, and synaptic plasticity. The activation of TrkB by ligands initiates downstream signaling pathways that regulate essential cellular processes, making TrkB a key player in understanding neurological diseases and developing therapeutic interventions.

Product Image Gallery
Western blot analysis of extracts on SH-SY5Y, Mouse brain, Rat brain cells, using Phospho-TrkB (Tyr817) Rabbit Monoclonal Antibody (EAB21609) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 92 kDa; Observed band size: 92/145 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol