SKU-Pack Size | Availability | Size | Price | |
EAB21491-100UL | In Stock | 100ul | €297.70 | |
EAB21491-200UL | In Stock | 200ul | €479.70 |
Please select the country you are in to find your local distributor. |
OlaSciences | Phone£º+33 (0) 9 77 4001 556 | |
87, rue des Suisses 65000 Nanterre, | E-mail£ºola@olasciences.com | |
France | France | Web£ºwww.olasciences.com |
Product Information | |
Applications | WB, IP, IHC-P, IF/ICC, FC |
Species Reactivity | Human |
Host / Isotype | Rabbit IgG |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000¡¡ IP=1:10-100¡¡ IHC-P=1:50-200¡¡ IF/ICC=1:50-200¡¡ FC=1:10-100 |
MW (kDa) | 23 |
Conjugate | Unconjugate |
Specificity | Bak Rabbit Monoclonal Antibody detects endogenous levels of Bak protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | BAK; BAK-LIKE; BAK1; BCL2L7; CDN1; N-Bak |
Gene Aliases | BAK1 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using Bak Rabbit Monoclonal Antibody (EAB21491) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:10000 dilution.
Lane1: Hela Lane2: Human skeletal muscle |
Specific Protocols | |