Recombinant Antibodies - Phospho-PKR (Thr451) Rabbit Monoclonal Antibody

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Phospho-PKR (Thr451) Rabbit Monoclonal Antibody

Catalog #：EAB22684

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22684-100UL	In Stock	100ul	€336.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB
Species Reactivity	Human
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	62
Conjugate	Unconjugate
Specificity	Phospho-PKR (Thr451) Rabbit Monoclonal Antibody detects endogenous levels of PKR only when phosphorylated at Thr451.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Eukaryotic translation initiation factor 2 alpha kinase 2; PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83; EIF2AK2
Gene Aliases	EIF2AK2
UniProt ID	P19525
Entrez Gene ID	5610

Product Description

PKR also known as EIF2AK2 is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses.

Product Image Gallery
Western blot analysis of extracts on Hela cells treated with TNFalpha, using Phospho-PKR (Thr451) Rabbit Monoclonal Antibody (EAB22684) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide. Predicted band size: 62 kDa; Observed band size: 68 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol