Recombinant Antibodies - Cytokeratin 18 Rabbit Monoclonal Antibody

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Cytokeratin 18 Rabbit Monoclonal Antibody

Catalog #：EAB21398

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21398-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IHC-P=1:100-500　 IF/ICC=1:100-500
MW (kDa)	48
Conjugate	Unconjugate
Specificity	Cytokeratin 18 Rabbit Monoclonal Antibody detects endogenous levels of Cytokeratin 18 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Cytokeratin-18; keratin 18; K18; CK-18; CYK18; KRT18
Gene Aliases	KRT18
UniProt ID	P05783
Entrez Gene ID	3875

Product Description

Cytokeratin 18 also known as CK-18, Keratin 18, KRT18 is a vital component of the cytoskeleton in epithelial cells, Cytokeratin 18 playing a crucial role in maintaining cell integrity and providing mechanical support. Cytokeratin 18 is primarily located in the cytoplasm of epithelial cells, where proper localization is essential for cellular architecture and function. Disruption of Cytokeratin 18 localization can lead to compromised cell stability and has been implicated in various pathological conditions, including cancer. Cytokeratin 18 serves as a significant marker for adenocarcinomas and basal cell carcinomas, making Cytokeratin 18 an important target for cancer diagnostics and research.

Product Image Gallery
Western blot analysis of extracts on HepG2, A431, Rat liver cells, using Cytokeratin 18 Rabbit Monoclonal Antibody (EAB21398) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol