Recombinant Antibodies - Bax Rabbit Monoclonal Antibody

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Bax Rabbit Monoclonal Antibody

Catalog #：EAB22188

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22188-100UL	In Stock	100ul	￡251.90

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IP, IHC-P, FC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IP=1:10-100　 IHC-P=1:100-500　　 FC=1:10-100
MW (kDa)	21
Conjugate	Unconjugate
Specificity	Bax Rabbit Monoclonal Antibody detects endogenous levels of Bax protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	BCL2 associated X; BCL2L4; BAX
Gene Aliases	BAX
UniProt ID	Q07812
Entrez Gene ID	581

Product Description

Bax belongs to the BCL2 protein family. Bax is primarily located in the cytosol and translocates to the mitochondria during the early stages of apoptosis, where Bax facilitates the release of cytochrome c, a key event that triggers the apoptotic cascade. Understanding the localization and function of Bax is vital, as Bax activity is tightly regulated by interactions with anti-apoptotic proteins like Bcl-2, which can inhibit pro-apoptotic effects. The balance between Bax and Bcl-2 is critical for maintaining cellular homeostasis, and dysregulation of this balance can lead to various diseases, including cancer.

Product Image Gallery
Western blot analysis of extracts on Hela, MCF7, Human liver cells, using Bax Rabbit Monoclonal Antibody (EAB22188) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol