SKU-Pack Size | Availability | Size | Price | |
EAB21357-100UL | In Stock | 100ul | ¥2290.00 | |
EAB21357-200UL | In Stock | 200ul | ¥3690.00 |
Please select the country you are in to find your local distributor. |
北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IF/ICC, FC |
Species Reactivity | Human |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000 IF/ICC=1:100-500 FC=1:50-200 |
MW (kDa) | 106 |
Conjugate | Unconjugate |
Specificity | Rb Mouse Monoclonal Antibody detects endogenous levels of Rb protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | OSRC; p105-Rb; pp110; PPP1R130; pRb; RB; Rb-1; RB1 |
Gene Aliases | RB1 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using Rb Mouse Monoclonal Antibody (EAB21357) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: Jurkat Lane2: A431 |
Specific Protocols | |