Recombinant Antibodies - IRF-1 Rabbit Monoclonal Antibody

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IRF-1 Rabbit Monoclonal Antibody

Catalog #：EAB21351

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21351-100UL	In Stock	100ul	$343.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC, FC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IP=1:10-100　 IHC-P=1:50-200　 IF/ICC=1:50-200　 FC=1:10-100
MW (kDa)	37
Conjugate	Unconjugate
Specificity	IRF-1 Rabbit Monoclonal Antibody detects endogenous levels of IRF-1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Interferon regulatory factor 1; MAR; IRF-1; IMD117; IRF1
Gene Aliases	IRF1
UniProt ID	P10914
Entrez Gene ID	3659

Product Description

IRF-1(interferon regulatory factor 1) also known as MAR, IDM117 is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. IRF-1 plays a crucial role in the immune response by acting as a transcriptional activator for type I interferon genes, which are essential for the antiviral response and regulation of immune cell activity. IRF-1 is primarily located in the nucleus, where IRF-1 binds to specific DNA sequences in the promoters of interferon-α and interferon-β genes, facilitating their transcription. This nuclear localization enables IRF-1 to exert regulatory effects on gene expression in response to viral infections and other immune stimuli.

Product Image Gallery
Western blot analysis of extracts on Jurkat, PC12 cells, using IRF1 Rabbit Monoclonal Antibody (EAB21351) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 37 kDa; Observed band size: 48 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol