Recombinant Antibodies - SHP-1 Rabbit Monoclonal Antibody

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SHP-1 Rabbit Monoclonal Antibody

Catalog #：EAB22576

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22576-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC, FC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IP=1:10-100　 IHC-P=1:50-200　 IF/ICC=1:50-200　 FC=1:10-100
MW (kDa)	68
Conjugate	Unconjugate
Specificity	SHP-1 Rabbit Monoclonal Antibody detects endogenous levels of SHP-1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Protein tyrosine phosphatase non-receptor type 6; HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1; PTPN6
Gene Aliases	PTPN6
UniProt ID	P29350
Entrez Gene ID	5777

Product Description

SHP-1 also known as SH-PTP1, PTPN6 is a member of the protein tyrosine phosphatase (PTP) family. SHP-1 plays a crucial role in regulating cellular signaling pathways by dephosphorylating tyrosine residues on target proteins, which is essential for maintaining the balance of tyrosine phosphorylation in cells. This regulation is particularly important in hematopoietic cells, where SHP-1 modulates the activity of various signaling pathways involved in cell growth, differentiation, and immune responses. The presence of two SH2 domains in SHP-1 enables interaction with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby influencing the downstream signaling events that are critical for cellular function.

Product Image Gallery
Western blot analysis of extracts on Hela, Jurkat, Raw264.7 cells, using SHP-1 Rabbit Monoclonal Antibody (EAB22576) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:10000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol