Recombinant Antibodies - MEK1/2 Rabbit Monoclonal Antibody

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MEK1/2 Rabbit Monoclonal Antibody

Catalog #：EAB21436

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21436-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IP=1:10-100　 IHC-P=1:100-500　 IF/ICC=1:100-500
MW (kDa)	43, 44
Conjugate	Unconjugate
Specificity	MEK1/2 Rabbit Monoclonal Antibody detects endogenous levels of MEK1/2 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Mitogen-activated protein kinase kinase 1; Mitogen-activated protein kinase kinase 2; MEL; CFC3; MEK1; MKK1; MAPKK1; PRKMK1; MAP2K1; CFC4; MEK2; MKK2; MAPKK2; PRKMK2; MAP2K2
Gene Aliases	MAP2K1/MAP2K2
UniProt ID	P36507, Q02750
Entrez Gene ID	5605, 5604

Product Description

MEK1 also known as MKK1, MAP2K1 and MEK2 also known as MKK2, MAP2K2 are dual specificity protein kinase that belongs to the MAP kinase kinase family. MEK1 and MEK2 play a crucial role in the mitogen-activated protein kinase (MAPK) signaling pathway, essential for various cellular processes, including proliferation, differentiation, and survival. MEK1 and MEK2 proteins are located in the cytoplasm and activate in response to extracellular signals, leading to phosphorylation of downstream MAP kinases such as ERK. Proper functioning of MEK1 and MEK2 remains vital, as dysregulation of this pathway can contribute to various diseases, including cancer. MEK1 and MEK2 interact with other proteins in the signaling cascade, such as Raf kinases, further underscoring their importance in cellular signaling networks.

Product Image Gallery
Western blot analysis of extracts on Hela, K562 cells, using MEK1/2 Rabbit Monoclonal Antibody (EAB21436) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol