P01137

TGF-β1 also known as TGF beta1, TGFB1 plays a crucial role in regulating various cellular processes, including cell growth, differentiation, and immune responses, making TGFβ1 essential for maintaining tissue homeostasis and mediating healing processes. TGFβ1 is primarily secreted by platelets and various cell types, including macrophages and fibroblasts, and exists in the extracellular matrix, where TGFβ1 influences surrounding cell behavior. TGFβ1′s location in the extracellular space enables interaction with specific receptors on target cells, initiating signaling cascades that lead to diverse biological outcomes, such as fibrosis or immune suppression. Understanding TGFβ1 dynamics and interactions is vital for developing therapeutic strategies for diseases characterized by dysregulated TGFβ signaling, such as cancer and autoimmune disorders.