P00338

LDHA(Lactate dehydrogenase A) plays a crucial role in cellular metabolism by catalyzing the conversion of L-lactate to pyruvate, a key step in anaerobic glycolysis, which is vital for energy production, especially in tissues with high energy demands like muscle. LDHA serves as a significant biomarker for various conditions, including germ cell tumors, where expression levels can indicate tumor presence and progression. LDHA is predominantly expressed in muscle tissue, highlighting a role in energy production during intense physical activity. The gene encoding LDHA is located on chromosome 11, and mutations or deficiencies in this gene can lead to conditions such as exertional myoglobinuria, underscoring LDHA′s importance in both health and disease.