Polyclonal Antibodies - Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody

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Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody

Catalog #：EAB14301

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14301-30UL	In Stock	30ul	€141.70
EAB14301-100UL	In Stock	100ul	€297.70
EAB14301-200UL	In Stock	200ul	€479.70

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email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	131
Conjugate	Unconjugate
Specificity	Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody detects endogenous levels of HDAC6 protein only when phosphorylated at Ser22.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Histone deacetylase 6; HD6; JM21; CPBHM; KDAC6; PPP1R90; HDAC6
Gene Aliases	HDAC6
UniProt ID	Q9UBN7
Entrez Gene ID	10013

Product Description

HDAC6(Histone deacetylase 6) is a member of the histone deacetylase family. HDAC6 plays a crucial role in regulating cellular processes by deacetylating non-histone proteins, which influences various signaling pathways and cellular functions. HDAC6 recognizes a protein involved in cytoskeleton regulation and essential for proper microtubule functioning, which are vital for cell shape, motility, and intracellular transport. HDAC6′s ability to interact with and deacetylate tubulin highlights its importance in maintaining cellular architecture and function. Dysregulation of HDAC6 has been implicated in several diseases, including cancer and neurodegenerative disorders, making HDAC6 a significant target for therapeutic intervention.

Product Image Gallery

Western blot analysis of extracts on NIH/3T3 cells treated with Anisomycin, using Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody (EAB14301) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.

Immunohistochemistry analysis of paraffin-embedded Human testis tissue, using Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody (EAB14301) at 1:200 dilution.

Immunofluorescence analysis of HepG2 cell, using Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody (EAB14301) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol