SKU-Pack Size | Availability | Size | Price | |
EAB14708-30UL | In Stock | 30ul | ¥890.00 | |
EAB14708-100UL | In Stock | 100ul | ¥1990.00 | |
EAB14708-200UL | In Stock | 200ul | ¥3390.00 |
Please select the country you are in to find your local distributor. |
北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IHC-P, IF/ICC, ELISA |
Species Reactivity | Human, Mouse, Rat, Monkey |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
MW (kDa) | 49 |
Conjugate | Unconjugate |
Specificity | HDAC3 Rabbit Polyclonal Antibody detects endogenous levels of HDAC3 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | RPD32; RPD3-2; HD-3; HD3; HDAC-3; RPD3; SMAP 45; SMAP-45; SMAP45; HDAC3; KDAC3; Histone deacetylase 3 |
Gene Aliases | HDAC3 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using HDAC3 Rabbit Polyclonal Antibody (EAB14708) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: NIH/3T3 Lane2: K562 Lane3: Jurkat Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using HDAC3 Rabbit Polyclonal Antibody (EAB14708) at 1:200 dilution.
Immunofluorescence analysis of COS7 cell, using HDAC3 Rabbit Polyclonal Antibody (EAB14708) at 1:200 dilution.
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Specific Protocols | |