Monoclonal Antibodies - ABCB5 Mouse Monoclonal Antibody

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ABCB5 Mouse Monoclonal Antibody

Catalog #：EAB11923

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11923-30UL	In Stock	30ul	€115.70
EAB11923-100UL	In Stock	100ul	€258.70
EAB11923-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, IF/ICC
Species Reactivity	Human
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IHC-P=1:100-500　 IF/ICC=1:50-300
MW (kDa)	90
Conjugate	Unconjugate
Specificity	ABCB5 Mouse Monoclonal Antibody detects endogenous levels of ABCB5 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	ABCB-5; ABCB5; ABCB5alpha; ABCB5beta; EST422562; RGD1566342; ATP-binding cassette sub-family B member 5
Gene Aliases	ABCB5
UniProt ID	Q2M3G0
Entrez Gene ID	340273

Product Description

ABCB5 (ATP-binding cassette sub-family B member 5), also known as P-glycoprotein ABCB5 or ABCB5 P-gp, is a 812 amino acid multi-pass membrane protein that belongs to the superfamily of ABC transporters. Expressed ubiquitously, ABCB5 contains two ABC transporter domains and one ABC transmembrane type-1 domain and is responsible for the resistance to doxorubicin of a subset of malignant melanomas. It is suggested ABCB5 inhibits tumor growth and is thought to be a novel drug transporter and chemoresistance mediator in melanoma cells. Two isoforms of ABCB5, designated alpha and beta, exist due to alternative splicing events.

Product Image Gallery
Western blot analysis of extracts on Hela, 293T cells, using ABCB5 Mouse Monoclonal Antibody (EAB11923) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human breast caricnoma tissue, using ABCB5 Mouse Monoclonal Antibody (EAB11923) at 1:500 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol