Polyclonal Antibodies - Cleaved-Caspase-2 p18 (Gly170) Rabbit Polyclonal Antibody

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Cleaved-Caspase-2 p18 (Gly170) Rabbit Polyclonal Antibody

Catalog #：EAB14657

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14657-30UL	In Stock	30ul	￡119.90
EAB14657-100UL	In Stock	100ul	￡251.90
EAB14657-200UL	In Stock	200ul	￡405.90

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	51
Conjugate	Unconjugate
Specificity	Cleaved-Caspase-2 p18 (Gly170) Rabbit Polyclonal Antibody detects endogenous levels of Caspase-2 p18 protein only when cleaved at Gly170.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	CASP-2; CASP2; ICH-1; ICH1; NEDD-2; NEDD2; PPP1R57
Gene Aliases	CASP2
UniProt ID	P42575
Entrez Gene ID	835

Product Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Product Image Gallery
Western blot analysis of extracts on Jurkat cells, using Cleaved-Caspase-2 p18 (Gly170) Rabbit Polyclonal Antibody (EAB14657) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 51 kDa; Observed band size: 18,35 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol