Rad51D also known as TRAD, R51H3 is a member of the RAD51 protein family. Rad51D plays an essential role in the homologous recombination repair (HRR) pathway that is responsible for repairing DNA double-strand breaks and maintaining genomic stability. Structurally, Rad51D forms part of the BCDX2 complex alongside Rad51B, Rad51C, and XRCC2, which is crucial for the detection and repair of DNA damage by facilitating the formation and stabilization of RAD51 nucleoprotein filaments necessary for effective homologous recombination. Post-translational modifications of Rad51D, such as phosphorylation and ubiquitination, are vital for regulating activity, interactions, and cellular localization, thereby ensuring efficient participation in DNA repair processes.