Polyclonal Antibodies - Phospho-IGFIR (Tyr1165/1166) Rabbit Polyclonal Antibody

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Phospho-IGFIR (Tyr1165/1166) Rabbit Polyclonal Antibody

Catalog #：EAB14623

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14623-30UL	In Stock	30ul	￡119.90
EAB14623-100UL	In Stock	100ul	￡251.90
EAB14623-200UL	In Stock	200ul	￡405.90

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat, Monkey
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	155
Conjugate	Unconjugate
Specificity	Phospho-IGFIR (Tyr1165/1166) Rabbit Polyclonal Antibody detects endogenous levels of IGFIR only when phosphorylated at Tyr1165/1166.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Insulin like growth factor 1 receptor; IGFR; CD221; IGFIR; JTK13; IGF1R
Gene Aliases	IGF1R
UniProt ID	P08069
Entrez Gene ID	3480

Product Description

IGFIR is a transmembrane receptor tyrosine kinase that is widely expressed in many cell lines and cell types within fetal and postnatal tissues. The activated IGFIR is involved in cell growth and survival control. IGFIR is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins.

Product Image Gallery
Western blot analysis of extracts on 293 cells treated with Insulin, using Phospho-IGFIR (Tyr1165/1166) Rabbit Polyclonal Antibody (EAB14623) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide. Predicted band size: 155 kDa; Observed band size: 95,155 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol