Polyclonal Antibodies - Phospho-IRF-3 (Ser386) Rabbit Polyclonal Antibody

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Phospho-IRF-3 (Ser386) Rabbit Polyclonal Antibody

Catalog #：EAB14345

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14345-30UL	In Stock	30ul	€141.70
EAB14345-100UL	In Stock	100ul	€297.70
EAB14345-200UL	In Stock	200ul	€479.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, IHC-P
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300
MW (kDa)	47
Conjugate	Unconjugate
Specificity	Phospho-IRF-3 (Ser386) Rabbit Polyclonal Antibody detects endogenous levels of IRF-3 protein only when phosphorylated at Ser386.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Interferon regulatory factor 3; IIAE7; IRF3
Gene Aliases	IRF3
UniProt ID	Q14653
Entrez Gene ID	3661

Product Description

IRF-3 is a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.

Product Image Gallery
Western blot analysis of extracts on HepG2 cells treated with EGF, using Phospho-IRF-3 (Ser386) Rabbit Polyclonal Antibody (EAB14345) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide. Predicted band size: 47 kDa; Observed band size: 45-55 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol