Polyclonal Antibodies - LRP6 Rabbit Polyclonal Antibody

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LRP6 Rabbit Polyclonal Antibody

Catalog #：EAB13820

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13820-30UL	In Stock	30ul	€115.70
EAB13820-100UL	In Stock	100ul	€258.70
EAB13820-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	180
Conjugate	Unconjugate
Specificity	LRP6 Rabbit Polyclonal Antibody detects endogenous levels of LRP6 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	LDL receptor related protein 6; EVR8; OPTA4; ADCAD2; STHAG7; LRP6
Gene Aliases	LRP6
UniProt ID	O75581
Entrez Gene ID	4040

Product Description

LRP6 is a member of the low density lipoprotein (LDL) receptor gene family. LRP6 plays a crucial role in mediating Wnt/β-catenin signaling, a pathway essential for numerous developmental processes such as body axis patterning, central nervous system development, limb formation, and organogenesis. This signaling pathway is vital for maintaining cellular functions and tissue homeostasis, and dysregulation of LRP6 has been implicated in various diseases, including cancer and metabolic disorders. The human LRP6 gene is located on chromosome 12p13.2 and encodes a protein characterized by a unique arrangement of four epidermal growth factor (EGF) repeats and three low-density lipoprotein receptor (LDLR) repeats in its extracellular domain, which are critical for its interaction with Wnt ligands.

Product Image Gallery
Western blot analysis of extracts on SH-SY5Y cells, using LRP6 Rabbit Polyclonal Antibody (EAB13820) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol