Polyclonal Antibodies - Phospho-PAK5/PAK6 (Ser602/Ser560) Rabbit Polyclonal Antibody

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Phospho-PAK5/PAK6 (Ser602/Ser560) Rabbit Polyclonal Antibody

Catalog #：EAB11869

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11869-30UL	In Stock	30ul	€141.70
EAB11869-100UL	In Stock	100ul	€297.70
EAB11869-200UL	In Stock	200ul	€479.70

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	75, 81
Conjugate	Unconjugate
Specificity	Phospho-PAK5/PAK6 (Ser602/Ser560) Rabbit Polyclonal Antibody detects endogenous levels of PAK5/PAK6 only when phosphorylated at Ser602/560.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	p21 (RAC1) activated kinase 5; p21 (RAC1) activated kinase 6; PAK7; PAK-5; PAK-6; PAK-7; PAK5; PAK6
Gene Aliases	PAK6/PAK7
UniProt ID	Q9P286, Q9NQU5
Entrez Gene ID	57144, 56924

Product Description

PAK5/PAK6 is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Product Image Gallery
Western blot analysis of extracts on LOVO cells treated with PMA, using Phospho-PAK5/PAK6 (Ser602/Ser560) Rabbit Polyclonal Antibody (EAB11869) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol