Polyclonal Antibodies - Phospho-Sin1 (Thr86) Rabbit Polyclonal Antibody

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Phospho-Sin1 (Thr86) Rabbit Polyclonal Antibody

Catalog #：EAB10855

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB10855-30UL	In Stock	30ul	€141.70
EAB10855-100UL	In Stock	100ul	€297.70
EAB10855-200UL	In Stock	200ul	€479.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, IHC-P, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300
MW (kDa)	59
Conjugate	Unconjugate
Specificity	Phospho-Sin1 (Thr86) Rabbit Polyclonal Antibody detects endogenous levels of Sin1 protein only when phosphorylated at Thr86.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	MAPKAP-1; MAPKAP1; MEKK2 interacting protein 1; MGC2745; MIP-1; MIP1; Mitogen activated protein kinase associated protein 1; JC310
Gene Aliases	MAPKAP1
UniProt ID	Q9BPZ7
Entrez Gene ID	79109

Product Description

Sin1 also designated MAPKAP-1 is a protein that localizes in the nucleus and is involved in several different signal transduction pathways. MAPKAP-1 contains one stress-activated map kinase interacting 1 domain (Pfam), a 2nd peroximal domain, and an ER membrane domain (Psort2). MAPKAP-1 binds to and inhibits c-Jun N-terminal kinase (JNK), and may act as a scaffold molecule in the regulation of JNK signaling. Transcription of the MAPKAP-1 gene is activated any time the organism is wounded, and stress to the cell causes the MAPKAP-1 protein to be phosphorylated. Cells lacking this protein may display sterility, multiple stress sensitivity, and a cell-cycle delay.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol