SKU-Pack Size | Availability | Size | Price | |
EAB10839-30UL | In Stock | 30ul | £119.90 | |
EAB10839-100UL | In Stock | 100ul | £251.90 | |
EAB10839-200UL | In Stock | 200ul | £405.90 |
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CUlabSciences | Phone:+44 (0) 1232 330008 | |
Cambridge House St Thomas' Place Ely, | E-mail:sales@culabsciences.co.uk | |
United Kingdom | Cambridge CB27 9RD UK | Web:www.culabsciences.co.uk |
Product Information | |
Applications | WB, IHC-P, IF, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
MW (kDa) | 58 |
Conjugate | Unconjugate |
Specificity | Phospho-LYN (Tyr507) Rabbit Polyclonal Antibody detects endogenous levels of LYN only when phosphorylated at Tyr507. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | LYN; JTK8; Tyrosine-protein kinase Lyn; Lck/Yes-related novel protein tyrosine kinase; p53Lyn; p56Lyn |
Gene Aliases | LYN |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT). |
Product Image Gallery | |
Western blot analysis of extracts on 293 cells, using Phospho-LYN (Tyr507) Rabbit Polyclonal Antibody (EAB10839) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 58 kDa; Observed band size: 53, 56 kDa |
Specific Protocols | |