| SKU-Pack Size | Availability | Size | Price | |
| EAB10827-30UL | In Stock | 30ul | €141.70 | |
| EAB10827-100UL | In Stock | 100ul | €297.70 | |
| EAB10827-200UL | In Stock | 200ul | €479.70 |
| Please select the country you are in to find your local distributor. |
| Betaclonal | Phone£º+34 (0)91 471 6763 | |
| 29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
| Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
| Product Information | |
| Applications | WB, IHC-P, IF, ELISA |
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit IgG |
| Clonality | Polyclonal |
| Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:50-300¡¡ IF=1:50-300 |
| MW (kDa) | 52 |
| Conjugate | Unconjugate |
| Specificity | Phospho-SRF (Ser103) Rabbit Polyclonal Antibody detects endogenous levels of SRF only when phosphorylated at Ser103. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
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| Product Bioinformatics | |
| Synonym(s) | Serum response factor; MCM1; SRF |
| Gene Aliases | SRF |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
SRF(Serum response factor) also known as MCM1 is a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. SRF is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. SRF binds to the serum response element (SRE) in the promoter region of target genes. SRF regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. SRF is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on LOVO cells treated with Serum, using Phospho-SRF (Ser103) Rabbit Polyclonal Antibody (EAB10827) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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| Specific Protocols | |