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Gab2 Rabbit Polyclonal Antibody
Catalog #£ºEAB10763
  SKU-Pack Size Availability Size Price
EAB10763-30UL In Stock 30ul €115.70
EAB10763-100UL In Stock 100ul €258.70
EAB10763-200UL In Stock 200ul €440.70
If you want to get a larger packsize, Please contact your local distributor or
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Product Information
Applications WB, IHC-P, IF, ELISA
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000¡¡
IHC-P=1:50-300
IF=1:50-300
MW (kDa) 74
Conjugate Unconjugate
Specificity Gab2 Rabbit Polyclonal Antibody detects endogenous levels of Gab2 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) GRB2 associated binding protein 2; GAB2
Gene Aliases GAB2
UniProt ID

Q9UQC2

Entrez Gene ID

9846

Product Description

Gab2 is a member of the GRB2-associated binding protein (GAB) gene family. Gab 2 protein plays a crucial role in cellular signaling pathways, particularly in growth factor receptor activation. Gab 2 functions as an adapter protein that facilitates signal transmission from activated receptor tyrosine kinases to downstream signaling molecules, influencing cellular responses such as proliferation and differentiation. Gab 2 interacts with SH2 domain-containing proteins, including SHP2, which is essential for mediating cytokine-induced gene activation. Such interaction links extracellular signals to intracellular responses, making Gab 2 vital for regulating various biological processes. Gab 2′s ability to form complexes with other signaling proteins orchestrates complex signaling networks, critical for maintaining cellular homeostasis and responding to environmental cues.

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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