SKU-Pack Size | Availability | Size | Price | |
EAB10632-30UL | In Stock | 30ul | $133.50 | |
EAB10632-100UL | In Stock | 100ul | $298.50 | |
EAB10632-200UL | In Stock | 200ul | $508.50 |
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EbioCell | Phone:(540) 808-3925 | |
Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
Canada | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
Product Information | |
Applications | WB, IF/ICC, ELISA |
Species Reactivity | Human, Mouse, Rat, Monkey |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IF/ICC=1:50-300 |
MW (kDa) | 120 |
Conjugate | Unconjugate |
Specificity | ATP-Citrate Lyase Rabbit Polyclonal Antibody detects endogenous levels of ATP-Citrate Lyase protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | ATP citrate (pro-S) lyase; ATP citrate synthase; ACL; ACLY; ATPCL; AW538652; CLATP |
Gene Aliases | ACLY |
UniProt ID | |
Entrez Gene ID |
Product Description | |
ATP-citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using ATP-Citrate Lyase Rabbit Polyclonal Antibody (EAB10632) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: 293T Lane2: COS7 |
Specific Protocols | |