Polyclonal Antibodies - Phospho-GluA2/GluR-2 (Tyr876) Rabbit Polyclonal Antibody

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Phospho-GluA2/GluR-2 (Tyr876) Rabbit Polyclonal Antibody

Catalog #：EAB10621

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB10621-30UL	In Stock	30ul	€141.70
EAB10621-100UL	In Stock	100ul	€297.70
EAB10621-200UL	In Stock	200ul	€479.70

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300 IF=1:50-300
MW (kDa)	99
Conjugate	Unconjugate
Specificity	Phospho-GluA2/GluR-2 (Tyr876) Rabbit Polyclonal Antibody detects endogenous levels of GluA2/GluR-2 only when phosphorylated at Tyr876.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Glutamate ionotropic receptor AMPA type subunit 2; Glutamate receptor 2; GLUR2; GLURB; GluA2; HBGR2; NEDLIB; gluR-2; gluR-B; GluR-K2; GRIA2
Gene Aliases	GRIA2
UniProt ID	P42262
Entrez Gene ID	2891

Product Description

GluR-2 also known as GRIA2 is a critical component of the AMPA receptor complex, which mediates fast excitatory neurotransmission in the central nervous system. GluR-2 is primarily located in the postsynaptic membrane of neurons, where GluR-2 plays a vital role in synaptic plasticity, a fundamental mechanism underlying learning and memory. Proper functioning of GluR-2 is essential for maintaining synaptic strength and facilitating communication between neurons. Alterations in GluR-2 expression or function have been implicated in various neurological disorders, including epilepsy, schizophrenia, and neurodegenerative diseases, highlighting GluR-2′s significance in both normal brain function and disease pathology.

Product Image Gallery
Western blot analysis of extracts on HuvEc cells, using Phospho-GluA2/GluR-2 (Tyr876) Rabbit Polyclonal Antibody (EAB10621) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol