SKU-Pack Size | Availability | Size | Price | |
EAB10600-30UL | In Stock | 30ul | $133.50 | |
EAB10600-100UL | In Stock | 100ul | $298.50 | |
EAB10600-200UL | In Stock | 200ul | $508.50 |
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EbioCell | Phone:(540) 808-3925 |
Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
Canada | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
Product Information | |
Applications | WB, IHC-P, IF/ICC, ELISA |
Species Reactivity | Human, Mouse, Rat, Monkey |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
MW (kDa) | 23 |
Conjugate | Unconjugate |
Specificity | Bad Rabbit Polyclonal Antibody detects endogenous levels of Bad protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | BCL2 associated agonist of cell death; BBC2; BCL2L8; BAD |
Gene Aliases | BAD |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
Product Image Gallery | |
![]() Western blot analysis of extracts on HEK293, Mouse liver cells, using Bad Rabbit Polyclonal Antibody (EAB10600) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 18 kDa; Observed band size: 18-25 kDa ![]() Immunohistochemistry analysis of paraffin-embedded Human colon cancer tissue, using Bad Rabbit Polyclonal Antibody (EAB10600) at 1:100 dilution.
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Specific Protocols | |