United States| SKU-Pack Size | Availability | Size | Price | |
| EAB10500-30UL | In Stock | 30ul | $133.50 | |
| EAB10500-100UL | In Stock | 100ul | $298.50 | |
| EAB10500-200UL | In Stock | 200ul | $508.50 |
| Please select the country you are in to find your local distributor. |
| EbioCell | Phone:(540) 808-3925 | |
| Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
| United States | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
| Product Information | |
| Applications | WB, IHC-P, IF/ICC, ELISA |
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit IgG |
| Clonality | Polyclonal |
| Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| MW (kDa) | 28 |
| Conjugate | Unconjugate |
| Specificity | 14-3-3 beta Rabbit Polyclonal Antibody detects endogenous levels of 14-3-3 beta protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
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| Product Bioinformatics | |
| Synonym(s) | HS1; GW128; YWHAA; KCIP-1; HEL-S-1; 14-3-3 protein beta/alpha |
| Gene Aliases | YWHAB |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
14-3-3 beta is a protein belonging to the 14-3-3 family of proteins.14-3-3 beta protein plays a crucial role in regulating numerous cellular processes, particularly in cancer biology, where 14-3-3 beta protein is involved in apoptosis, mitogenic signaling, and cell-cycle checkpoints. 14-3-3 beta protein is primarily located in the cytoplasm, where 14-3-3 beta protein acts as a scaffold that facilitates the interaction of various signaling proteins, thereby influencing their activity and stability. This cytoplasmic localization allows 14-3-3 proteins to sequester target proteins, preventing their degradation and modulating their functions in response to cellular signals. 14-3-3 proteins bind to phosphorylated serine and threonine residues, enabling regulation of a wide array of cellular pathways, and dysregulation can lead to significant pathological conditions, including cancer. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on MCF7, PC12, Hela cells, using 14-3-3 beta Rabbit Polyclonal Antibody (EAB10500) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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| Specific Protocols | |