SKU-Pack Size | Availability | Size | Price | |
EAB10490-30UL | In Stock | 30ul | $163.50 | |
EAB10490-100UL | In Stock | 100ul | $343.50 | |
EAB10490-200UL | In Stock | 200ul | $553.50 |
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EbioCell | Phone:(540) 808-3925 | |
Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
Canada | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
Product Information | |
Applications | WB, ELISA |
Species Reactivity | Human, Mouse |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 |
MW (kDa) | 34 |
Conjugate | Unconjugate |
Specificity | Cleaved-Caspase-7 (Asp198) Rabbit Polyclonal Antibody detects endogenous levels of caspase-7 protein only when cleaved at Asp198. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | CASP-7; CASP7; caspase-7; CMH-1; ICE-IAP3; ICE-LAP3; LICE2; mCASP-7; MCH3 |
Gene Aliases | CASP7 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Caspase-7 (also designated Mch3, ICE-LAP3, CMH-1) is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Product Image Gallery | |
Western blot analysis of extracts on Jurkat cells treated with Etoposide, using Cleaved-Caspase-7 (Asp198) Rabbit Polyclonal Antibody (EAB10490) at 1:1000 dilution. The lane on the left is blocked with the synthesized peptide.
Predicted band size: 34 kDa; Observed band size: 20 kDa |
Specific Protocols | |