Polyclonal Antibodies - PCNA Rabbit Polyclonal Antibody

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PCNA Rabbit Polyclonal Antibody

Catalog #：EAB10348

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB10348-30UL	In Stock	30ul	$133.50
EAB10348-100UL	In Stock	100ul	$298.50
EAB10348-200UL	In Stock	200ul	$508.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
Canada	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	29
Conjugate	Unconjugate
Specificity	PCNA Rabbit Polyclonal Antibody detects endogenous levels of PCNA protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Proliferating cell nuclear antigen; ATLD2; PCNA
Gene Aliases	PCNA
UniProt ID	P12004
Entrez Gene ID	5111

Product Description

PCNA(Proliferating cell nuclear antigen) is a critical nuclear protein involved in DNA replication and repair in eukaryotic cells. PCNA forms a ring structure that acts as a scaffold for recruiting proteins, supporting DNA polymerases during replication. PCNA plays key roles in DNA metabolism, chromatin remodeling, cell cycle regulation, and DNA repair pathways, ensuring high-fidelity DNA replication. PCNA is regulated by post-translational modifications, allowing dynamic response to DNA damage and maintenance of genomic integrity. Dysregulation of PCNA is linked to cancer, making PCNA an important biomarker for prognosis and a potential therapeutic target.

Product Image Gallery
Western blot analysis of extracts on HT29, HepG2, SW480 cells, using PCNA Rabbit Polyclonal Antibody (EAB10348) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue, using PCNA Rabbit Polyclonal Antibody (EAB10348) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol