SKU-Pack Size | Availability | Size | Price | |
EAB10229-30UL | In Stock | 30ul | €141.70 | |
EAB10229-100UL | In Stock | 100ul | €297.70 | |
EAB10229-200UL | In Stock | 200ul | €479.70 |
Please select the country you are in to find your local distributor. |
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Dianost | Phone£º+49 (0) 40 65472-053 |
Bullenkoppel 11£¬ 23896 Poggensee, | E-mail£ºola@olasciences.com | |
Germany | Germany | Web£ºwww.olasciences.com |
Product Information | |
Applications | WB, IP, IHC-P, IF/ICC, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000¡¡ IP=1:20-200¡¡ IHC-P=1:50-300¡¡ IF/ICC=1:50-300¡¡ |
MW (kDa) | 47 |
Conjugate | Unconjugate |
Specificity | Phospho-GSK-3¦Â (Ser9) Rabbit Polyclonal Antibody detects endogenous levels of GSK-3¦Â only when phosphorylated at Ser9. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | Glycogen synthase kinase 3 beta; GSK3¦Â; GSK3beta; GSK3B |
Gene Aliases | GSK3B |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine kinase that plays a crucial role in numerous signaling pathways, particularly those involved in glycogen metabolism and cellular adhesion, and has been linked to the pathogenesis of Alzheimer′s disease. GSK-3 exists in two isoforms, GSK-3α and GSK-3β, which differ in subcellular localization, with GSK-3α primarily found in the cytoplasm and GSK-3β localized in both the cytoplasm and nucleus. This differential localization is significant as GSK-3 may influence specific signaling pathways that each isoform regulates, thereby affecting cellular responses to various stimuli. |
Product Image Gallery | |
![]() Western blot analysis of extracts on Hela cells treated with EGF, using Phospho-GSK-3¦Â (Ser9) Rabbit Polyclonal Antibody (EAB10229) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
![]() Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using Phospho-GSK-3¦Â (Ser9) Rabbit Polyclonal Antibody (EAB10229) at 1:100 dilution.
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Specific Protocols | |