Polyclonal Antibodies - Phospho-Paxillin (Tyr31) Rabbit Polyclonal Antibody

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Phospho-Paxillin (Tyr31) Rabbit Polyclonal Antibody

Catalog #：EAB10224

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB10224-30UL	In Stock	30ul	€141.70
EAB10224-100UL	In Stock	100ul	€297.70
EAB10224-200UL	In Stock	200ul	€479.70

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email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF=1:50-300
MW (kDa)	65
Conjugate	Unconjugate
Specificity	Phospho-Paxillin (Tyr31) Rabbit Polyclonal Antibody detects endogenous levels of paxillin protein only when phosphorylated at Tyr31.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Paxillin; PAXI; PXN
Gene Aliases	PXN
UniProt ID	P49023
Entrez Gene ID	5829

Product Description

Paxillin also known as PXN is a focal adhesion phosphoprotein localized to the cytoskeleton. Paxillin plays a pivotal role in cell adhesion, migration, and signal transduction pathways. Paxillin′s interaction with focal adhesion kinase (FAK) is particularly important, as this interaction is essential for regulating tyrosine phosphorylation in response to cell adhesion. Phosphorylation of paxillin is a key event in signaling pathways activated by various growth factors and oncogenes, which can lead to significant changes in cell behavior, including migration and proliferation. Dynamic regulation of paxillin through tyrosine phosphorylation is vital for reorganizing the actin cytoskeleton, which is critical for maintaining cell shape and motility.

Product Image Gallery
Western blot analysis of extracts on Hela cells treated with TNF, using Phospho-Paxillin (Tyr31) Rabbit Polyclonal Antibody (EAB10224) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol