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Location：Home > Biochemicals > Protein Inhibitors
Nocodazole (CAS: 31430-18-9)
Catalog #：EBC51144
Datasheet
Nocodazole (CAS: 31430-18-9)
  SKU-Pack Size Availability Size Price
EBC51144-1ML In Stock 1mL(10mM in DMSO) ￥490.00
EBC51144-10MG In Stock 10mg ￥490.00
EBC51144-25MG In Stock 25mg ￥1190.00
EBC51144-50MG In Stock 50mg ￥1690.00
EBC51144-100MG In Stock 100mg ￥2690.00
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Product Information
Synonym(s) Nocodazolum, ChEMBL9514, Oncodazole,
Chemical Name methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
Application Nocodazole is a potent Tubulin production inhibitor, anti-neoplastic agent, and inhibitor of mitosis
CAS Number 31430-18-9
Purity ≥98.0%
Molecular Weight 301.32
Molecular Formula C₁₄H₁₁N₃O₃S
SMILES COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
Target & IC50 Abl: IC50 = 0.21μM
Solubility DMSO: 20 mg/mL (66.37 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 3.3187 ml 16.5937 ml 33.1873 ml
5 mM 0.6637 ml 3.3187 ml 6.6375 ml
10 mM 0.3319 ml 1.6594 ml 3.3187 ml
50 mM 0.0664 ml 0.3319 ml 0.6637 ml
Shipping Room Temperature
Storage Room Temperature
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Nocodazole is a rapidly-reversible inhibitor of microtubule polymerization, also inhibits Abl, Abl (E255K) and Abl (T315I) with IC50 of 0.21 μM, 0.53 μM and 0.64 μM, respectively. Nocodazole will bind to β-Tb and block polymerization, arrest mammalian cells in mitosis and release them into cytokinesis and G1 as well as mis-regulate mitotic kinases.
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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