Other Biochemicals - Kartogenin (CAS: 4727-31-5)

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Kartogenin (CAS: 4727-31-5)

Catalog #：EBC51127

Datasheet

Kartogenin (CAS: 4727-31-5)

SKU-Pack Size	Availability	Size	Price
EBC51127-1ML	In Stock	1mL(10mM in DMSO)	￥590.00
EBC51127-5MG	In Stock	5mg	￥490.00
EBC51127-10MG	In Stock	10mg	￥590.00
EBC51127-25MG	In Stock	25mg	￥1390.00
EBC51127-50MG	In Stock	50mg	￥1990.00

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Product Information

Synonym(s)

KGN

Chemical Name

2-[([1,1'-Biphenyl]-4-ylamino)carbonyl]benzoic acid

Application

Kartogenin is an inducing factor of mesenchymal stem cells into chondrocytes

CAS Number

4727-31-5

Purity

≥98.0%

Molecular Weight

317.34

Molecular Formula

C₂₀H₁₅NO₃

SMILES

C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O

Target & IC50

Smad4, Smad5

Solubility

DMSO: 63 mg/mL (198.52 mM)

Preparing Stock Solutions

ConcentrationSolventMass	1 mg	5 mg	10 mg
1 mM	3.1512 ml	15.7560 ml	31.5119 ml
5 mM	0.6302 ml	3.1512 ml	6.3024 ml
10 mM	0.3151 ml	1.5756 ml	3.1512 ml
50 mM	0.0630 ml	0.3151 ml	0.6302 ml

Shipping

Room Temperature

Storage

Room Temperature

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
Kartogenin binds to filamin A, an actin-binding protein, and inhibits its interaction with core-binding factor Beta. This interaction is reported to induce cartilage differentiation and potently induce human mesenchymal stem cells into chondrocytes.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol

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