Other Biochemicals - Kartogenin (CAS: 4727-31-5)

Kartogenin (CAS: 4727-31-5)

Catalog #：EBC51127

Kartogenin (CAS: 4727-31-5)

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Product Information

Synonym(s)

KGN

Chemical Name

2-[([1,1'-Biphenyl]-4-ylamino)carbonyl]benzoic acid

Application

Kartogenin is an inducing factor of mesenchymal stem cells into chondrocytes

CAS Number

4727-31-5

Purity

≥98.0%

Molecular Weight

317.34

Molecular Formula

C₂₀H₁₅NO₃

SMILES

C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O

Target & IC50

Smad4, Smad5

Solubility

DMSO: 63 mg/mL (198.52 mM)

Preparing Stock Solutions

Shipping

Room Temperature

Storage

Room Temperature

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
Kartogenin binds to filamin A, an actin-binding protein, and inhibits its interaction with core-binding factor Beta. This interaction is reported to induce cartilage differentiation and potently induce human mesenchymal stem cells into chondrocytes.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol