Stat3 Inhibitor VI, S3I-201
(CAS: 501919-59-1) |
SKU-Pack Size | Availability | Size | Price | |
EBC51123-1ML | In Stock | 1mL(10mM in DMSO) | ¥490.00 | |
EBC51123-5MG | In Stock | 5mg | ¥490.00 | |
EBC51123-10MG | In Stock | 10mg | ¥690.00 | |
EBC51123-25MG | In Stock | 25mg | ¥1290.00 | |
EBC51123-50MG | In Stock | 50mg | ¥1590.00 |
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北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |||||||||||||||||||||
Synonym(s) | NSC 74859, NSC-74859, S3I201 | ||||||||||||||||||||
Chemical Name | 2-Hydroxy-4-[[2-(4-methylphenyl)sulfonyloxyacetyl]amino]benzoic acid | ||||||||||||||||||||
Application | Stat3 Inhibitor VI, S3I-201 is an inhibitor of Stat3 phosphorylation and dimerization | ||||||||||||||||||||
CAS Number | 501919-59-1 | ||||||||||||||||||||
Purity | ≥99.0% | ||||||||||||||||||||
Molecular Weight | 365.36 | ||||||||||||||||||||
Molecular Formula | C₁₆H₁₅NO₇S | ||||||||||||||||||||
SMILES | CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O | ||||||||||||||||||||
Target & IC50 | Stat3: IC50 = 86 μM | ||||||||||||||||||||
Solubility | DMSO: 36.5 mg/mL (100 mM) | ||||||||||||||||||||
Preparing Stock Solutions |
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Shipping | Gel Pack | ||||||||||||||||||||
Storage | Store at -20°C | ||||||||||||||||||||
Research Use | For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use. |
Product Description | |
S31-201 is benezoic acid based small molecule, which inhibits the Stat3 transcription factor by blocking the phosphorylation and dimerization events necessary For activation. Many cancers express aberrant behavior in the Stat3 growth factor, making this compound a valuable tool For perturbing the chemistry of such systems. |
Specific Protocols | |