IWP-3 (CAS: 687561-60-0)
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SKU-Pack Size | Availability | Size | Price | |
EBC51121-5MG | In Stock | 5mg | €128.70 | |
EBC51121-10MG | In Stock | 10mg | €206.70 | |
EBC51121-25MG | In Stock | 25mg | €427.70 | |
EBC51121-50MG | In Stock | 50mg | €648.70 | |
EBC51121-100MG | In Stock | 100mg | €1038.70 |
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Product Information | |
Synonym(s) | Inhibitor of Wnt Production-3, IWP3, IWP 3 |
Chemical Name | 2-[[3-(4-fluorophenyl)-3,4,6,7-tetrahydro-4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-N-(6-methyl-2-benzothiazolyl)-acetamide |
Application | IWP-3 is an inhibitor of Wnt production |
CAS Number | 687561-60-0 |
Purity | ¡Ý98.0% |
Molecular Weight | 484.59 |
Molecular Formula | C₂₂H₁₇FN₄O₂S₃ |
SMILES | O=C(NC1=NC2=CC=C(C)C=C2S1)CSC3=NC(CCS4)=C4C(N3C5=CC=C(F)C=C5)=O |
Target & IC50 | Wnt: IC50 = 40 nM |
Solubility | DMSO: 2 mg/ml |
Shipping | Gel Pack |
Storage | Store at -20¡ãC |
Research Use | For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use. |
Product Description | |
IWP-3 is a Wnt pathway inhibitor by inactivating the Porcupine O-acyltransferase which palmitoylates Wnt proteins. It is reported to inhibit embryonic stem cell self-renewal and promote cardiomyocyte differentiation from human stem cells. |
Specific Protocols | |