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IQ-1 (CAS: 331001-62-8)
Catalog #：EBC51119
IQ-1 (CAS: 331001-62-8)
  SKU-Pack Size Availability Size Price
EBC51119-1ML In Stock 1mL(10mM in DMSO) ￥590.00
EBC51119-1MG In Stock 1mg ￥390.00
EBC51119-5MG In Stock 5mg ￥590.00
EBC51119-10MG In Stock 10mg ￥790.00
EBC51119-25MG In Stock 25mg ￥1590.00
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Product Information
Synonym(s) IQ1, Wnt pathway activator
Chemical Name 2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)acetamide
Application IQ-1 is a cell-permeable tetrahydroisoquinolinylidene
CAS Number 331001-62-8
Purity ≥98.0%
Molecular Weight 362.42
Molecular Formula C21H22N4O2
SMILES CC(=O)C1=CC=C(C=C1)N=NC(C2C3=CC=CC=C3CC(N2)(C)C)C(=O)N
Target & IC50 β-catenin/p300
Solubility DMSO: 72 mg/mL (198.66 mM)
Ethanol: 7 mg/mL (19.31 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.7592 ml 13.7961 ml 27.5923 ml
5 mM 0.5518 ml 2.7592 ml 5.5185 ml
10 mM 0.2759 ml 1.3796 ml 2.7592 ml
50 mM 0.0552 ml 0.2759 ml 0.5518 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

IQ-1 is a selective inhibitor of Beta-catenin/p300 signaling by binding to protein phosphatase 2. It is used to maintain embryonic cell pluripotency in Wnt3a-treated cells and prevent spontaneous differentiation. It is also reported to upregulate the expression of Sox2 and Oct4 transcription factors. 
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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