Protein Inhibitors - Cariporide (CAS: 159138-80-4)

Cariporide (CAS: 159138-80-4)

Catalog #：EBC51114

Cariporide (CAS: 159138-80-4)

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Product Information

Synonym(s)

HOE-642, HOE 642

Chemical Name

N-(Diaminomethylene)-4-isopropyl-3-(methylsulfonyl)benzamide

Application

Cariporide is an NHE-1 inhibitor that blocks apoptosis in cardiac muscle cells

CAS Number

159138-80-4

Purity

≥98.0%

Molecular Weight

283.35

Molecular Formula

C₁₂H₁₇N₃O₃S

SMILES

DMSO: 79 mg/mL (278.8 mM)

Target & IC50

Sodium/hydrogen exchanger : IC50 = 26 nM

Solubility

DMSO: 79 mg/mL (278.8 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
Cariporide (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1).

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol