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IDE2 (CAS: 1136466-93-7)
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Catalog #：EBC51111
Datasheet
IDE2 (CAS: 1136466-93-7)
  SKU-Pack Size Availability Size Price
EBC51111-1MG 2-4 Weeks 1mg ￥590.00
EBC51111-5MG 2-4 Weeks 5mg ￥1690.00
EBC51111-10MG 2-4 Weeks 10mg ￥2790.00
EBC51111-25MG 2-4 Weeks 25mg ￥4690.00
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Product Information
Synonym(s) 1DE 2, IDE-2
Chemical Name (Z)-7-(cyclopentylidenehydrazono)-7-hydroxyheptanoic acid
Application IDE2 is an inducer of stem cell differentiation
CAS Number 1136466-93-7
Purity ≥98.0%
Molecular Weight 240.30
Molecular Formula C12H20N2O3
SMILES C1CCC(=NNC(=O)CCCCCC(=O)O)C1
Target & IC50 endoderm formation inducer：EC5050 = 223 nM
Solubility DMSO: 24 mg/mL (100 mM)
Ethanol: 24 mg/mL (100 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 4.1615 ml 20.8073 ml 41.6146 ml
5 mM 0.8323 ml 4.1615 ml 8.3229 ml
10 mM 0.4162 ml 2.0807 ml 4.1615 ml
50 mM 0.0832 ml 0.4161 ml 0.8323 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

IDE2 activates the TGF-beta signaling pathway and induces definitive endoderm formation in human and mouse embryonic stem cells. It is also reported to increase the levels of Nodal expression, induce Smad2 phosphorylation and SOX17 expression. 
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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