Other Biochemicals - IDE2 (CAS: 1136466-93-7)

IDE2 (CAS: 1136466-93-7)

Catalog #：EBC51111

IDE2 (CAS: 1136466-93-7)

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Product Information

Synonym(s)

1DE 2, IDE-2

Chemical Name

(Z)-7-(cyclopentylidenehydrazono)-7-hydroxyheptanoic acid

Application

IDE2 is an inducer of stem cell differentiation

CAS Number

1136466-93-7

Purity

≥98.0%

Molecular Weight

240.30

Molecular Formula

C12H20N2O3

SMILES

C1CCC(=NNC(=O)CCCCCC(=O)O)C1

Target & IC50

endoderm formation inducer：EC5050 = 223 nM

Solubility

DMSO: 24 mg/mL (100 mM)
Ethanol: 24 mg/mL (100 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
IDE2 activates the TGF-beta signaling pathway and induces definitive endoderm formation in human and mouse embryonic stem cells. It is also reported to increase the levels of Nodal expression, induce Smad2 phosphorylation and SOX17 expression.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol