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IDE1 (CAS: 1160927-48-9)
Catalog #：EBC51110
Datasheet
IDE1 (CAS: 1160927-48-9)
  SKU-Pack Size Availability Size Price
EBC51110-1ML In Stock 1mL(10mM in DMSO) ￥890.00
EBC51110-1MG In Stock 1mg ￥490.00
EBC51110-5MG In Stock 5mg ￥1090.00
EBC51110-10MG In Stock 25mg ￥1790.00
EBC51110-25MG In Stock 50mg ￥3090.00
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Product Information
Synonym(s) IDE 1, IDE-1, endoderm formation inducer
Chemical Name 2-((E)-((Z)-(6-carboxy-1-hydroxyhexylidene)hydrazono)methyl)benzoic acid
Application IDE1 is an endoderm formation inducer
CAS Number 1160927-48-9
Purity ≥98.0%
Molecular Weight 306.31
Molecular Formula 1160927-48-9
SMILES C1=CC=C(C(=C1)/C=N\NC(=O)CCCCCC(=O)O)C(=O)O
Target & IC50 Induces definitive endoderm formation: EC5050 = 125 nM (ESCs)
Solubility DMSO: 30 mg/mL (97.94 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 3.2647 ml 16.3233 ml 32.6467 ml
5 mM 0.6529 ml 3.2647 ml 6.5293 ml
10 mM 0.3265 ml 1.6323 ml 3.2647 ml
50 mM 0.0653 ml 0.3265 ml 0.6529 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

IDE1 activates the TGF-beta signaling pathway and induces definitive endoderm formation in human and mouse embryonic stem cells. It is also reported to increase the levels of Nodal expression, induce Smad2 phosphorylation and SOX17 expression. 
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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