Other Biochemicals - IDE1 (CAS: 1160927-48-9)

IDE1 (CAS: 1160927-48-9)

Catalog #：EBC51110

IDE1 (CAS: 1160927-48-9)

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Product Information

Synonym(s)

IDE 1, IDE-1, endoderm formation inducer

Chemical Name

2-((E)-((Z)-(6-carboxy-1-hydroxyhexylidene)hydrazono)methyl)benzoic acid

Application

IDE1 is an endoderm formation inducer

CAS Number

1160927-48-9

Purity

≥98.0%

Molecular Weight

306.31

Molecular Formula

1160927-48-9

SMILES

C1=CC=C(C(=C1)/C=N\NC(=O)CCCCCC(=O)O)C(=O)O

Target & IC50

Induces definitive endoderm formation: EC5050 = 125 nM (ESCs)

Solubility

DMSO: 30 mg/mL (97.94 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
IDE1 activates the TGF-beta signaling pathway and induces definitive endoderm formation in human and mouse embryonic stem cells. It is also reported to increase the levels of Nodal expression, induce Smad2 phosphorylation and SOX17 expression.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol