Protein Inhibitors - HA-100 dihydrochloride (CAS: 210297-47-5)

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HA-100 dihydrochloride (CAS: 210297-47-5)

Catalog #：EBC51107

HA-100 dihydrochloride
(CAS: 210297-47-5)

SKU-Pack Size	Availability	Size	Price
EBC51107-5MG	In Stock	5mg	￥690.00
EBC51107-10MG	In Stock	10mg	￥1090.00
EBC51107-25MG	In Stock	25mg	￥2390.00

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	北京美瑞克生物科技有限公司	Phone： +86 010-62890160 / 13691184142(微信同号)
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China	Beijing China	Website： www.mrkbio.com

Product Information

Synonym(s)

AGN-PC-00L2ST, SCHEMBL5176161

Chemical Name

5-(1-piperazinylsulfonyl)-isoquinoline, dihydrochloride

Application

HA-100 is an inhibitor of protein kinases (PKs) including PKA, PKC, and PKG

CAS Number

210297-47-5

Purity

≥99.0%

Molecular Weight

350.26

Molecular Formula

C₁₃H₁₅N₃O₂S·2HCl

SMILES

C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl

Target & IC50

PKG: IC50 = 4 μM
PKA: IC50 = 8 μM
MLCK: IC50 = 240 μM

Solubility

DMSO: 20 mg/mL (57.10 mM)
H₂0: 70 mg/mL (199.85 mM)

Preparing Stock Solutions

ConcentrationSolventMass	1 mg	5 mg	10 mg
1 mM	2.8550 ml	14.2751 ml	28.5502 ml
5 mM	0.5710 ml	2.8550 ml	5.7100 ml
10 mM	0.2855 ml	1.4275 ml	2.8550 ml
50 mM	0.0571 ml	0.2855 ml	0.5710 ml

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
HA-100 is a protein kinase inhibitor, effecting PKA, PKC, and PKG. It is reported to aid in the survivability of pluripotent stem cells and useful in increasing the efficiency of the chemical reprogramming of human fibroblasts.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol

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