Protein Inhibitors - HA-100 dihydrochloride (CAS: 210297-47-5)

HA-100 dihydrochloride (CAS: 210297-47-5)

Catalog #：EBC51107

HA-100 dihydrochloride
(CAS: 210297-47-5)

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Product Information

Synonym(s)

AGN-PC-00L2ST, SCHEMBL5176161

Chemical Name

5-(1-piperazinylsulfonyl)-isoquinoline, dihydrochloride

Application

HA-100 is an inhibitor of protein kinases (PKs) including PKA, PKC, and PKG

CAS Number

210297-47-5

Purity

≥99.0%

Molecular Weight

350.26

Molecular Formula

C₁₃H₁₅N₃O₂S·2HCl

SMILES

C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl

Target & IC50

PKG: IC50 = 4 μM
PKA: IC50 = 8 μM
MLCK: IC50 = 240 μM

Solubility

DMSO: 20 mg/mL (57.10 mM)
H₂0: 70 mg/mL (199.85 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
HA-100 is a protein kinase inhibitor, effecting PKA, PKC, and PKG. It is reported to aid in the survivability of pluripotent stem cells and useful in increasing the efficiency of the chemical reprogramming of human fibroblasts.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol