USA：(540) 808-3925
China：400-117-0038
Order@ebiocell.com
China
Shopping Cart
Sign in \ Register
Hot Search：
Location：Home > Biochemicals > Protein Inhibitors
Go 6983 (CAS: 133053-19-7)
Catalog #：EBC51102
Go 6983 (CAS: 133053-19-7)
  SKU-Pack Size Availability Size Price
EBC51102-1ML In Stock 1mL(10mM in DMSO) ￥890.00
EBC51102-2MG In Stock 2mg ￥490.00
EBC51102-5MG In Stock 5mg ￥890.00
EBC51102-10MG In Stock 10mg ￥1490.00
EBC51102-25MG In Stock 25mg ￥2990.00
If you want to get a larger packsize, Please contact your local distributor or
email us atinfo@ebiocell.com
Please Select The Country You Are In To Find Your Local Distributor.
北京美瑞克生物科技有限公司 Phone：  +86 010-62890160 / 13691184142(微信同号)
2 / F, 128 malianwa North Road, Haidian District, E-mail：   mrkbio@163.com 
China Beijing China Website： www.mrkbio.com
Product Information
Synonym(s) Gö 6983, Goe 6983, Gouml 6983, inhibitor
Chemical Name 3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
Application Go 6983 is a PKC inhibitor that selectively inhibits PKC isoenzymes
CAS Number 133053-19-7
Purity ≥98.0%
Molecular Weight 442.50
Molecular Formula C₂₆H₂₆N₄O₃
SMILES CN(C)CCCN1C=C(C2=C1C=CC(=C2)OC)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
Target & IC50 PKCα: IC50 = 7 nM
PKCβ: IC50 = 7 nM
PKCγ: IC50 = 6 nM
PKCδ: IC50 = 10 nM
PKCζ: IC50 = 60 nM
Solubility DMSO: 88 mg/mL (198.87 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.2598 ml 11.2992 ml 22.5984 ml
5 mM 0.4520 ml 2.2598 ml 4.5197 ml
10 mM 0.2260 ml 1.1299 ml 2.2598 ml
50 mM 0.0452 ml 0.2260 ml 0.4520 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Go 6983 is a broad fast-acting inhibitor of various isoforms of protein kinase C. It can be used to inhibit differentiation and maintain the pluripotency of embryonic stem cells and enhance stem cell viability and growth. Go 6983 is also reported to exert cardio protective effects in myocardial ischemia and inhibited intracellular Ca accumulation. 
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
Antibodies
Primary Antibodies
Monoclonal Antibodies
Polyclonal Antibodies
Recombinant Antibodies
Secondary Antibodies
Antibody Panels
Biochemicals
Antibiotics
Protein Agonists, Antagonists and Activators
Protein Inhibitors
Protein Substrates
Stains, Dyes and Fluorescent Reagents
Other Biochemicals
Support Products
Cell Culture Related Agents
Specialty Cell Culture Media
Primary Cell Culture Media
Basal Cell Culture Media
Contact Us
Phone：919-816-2261
Fax：1-886-598-2438
Email：ebiocell@ebiocell.com
Address： Commercial Park West 2327 Englert Dr.
Room 101-5 Durham ,NC 27713
Copyright 2015 EbioCell, Inc. All Rights Reserved. 　备案号：津ICP备2022005142号-1