Protein Inhibitors - FTY720 (CAS: 162359-56-0)

FTY720 (CAS: 162359-56-0)

Catalog #：EBC51098

FTY720 (CAS: 162359-56-0)

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Product Information

Synonym(s)

Fingolimod hydrochloride, Fty-720, Fingolimod HCl

Chemical Name

2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride

Application

FTY720 is a cell-permeable immunosuppressive agent

CAS Number

162359-56-0

Purity

≥98.0%

Molecular Weight

343.93

Molecular Formula

C₁₉H₃₃ClNO₂·HCl

SMILES

CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N.Cl

Target & IC50

S1P receptor: IC50 = 0.03 nM

Solubility

DMSO : 100 mg/mL (290.76 mM) H₂O : 50 mg/mL (145.38 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
FTY720 is a sphingosine-1-phosphate receptor modulator that sequesters lymphocytes in lymph nodes, inhibiting their contribution to autoimmune responses. It is derived from myriocin (ISP-1), a fungal metabolite. FTY720 is also reported to be a cPLA2 inhibitor, a ceramide synthase inhibitor, and a cannabinoid receptor antagonist.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol